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Study Type, Agent, and Dose? After 3 hours After 24 hours Normal 111In-DTPA Cisternogram Agent: 111In-Diethylenetriamine Pentaacetic (DTPA) Adult Doses: 500 to 800 microCi intrathecally Critical Organ: Spinal Cord Notes:
Activity should reach the basal cisterns by 2 to 4 hours in adults
Activity should appear over the convexities of the brain by 24-28 hours; if it does not, further delayed imaging is necessary
Activity within the lateral ventricles at any time is considered abnormal
99mTc-DTPA is not used to evaluate CAF flow because of its short (6 hours). T1/2